Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GLI2 All Species: 0.3
Human Site: S1342 Identified Species: 0.74
UniProt: P10070 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10070 NP_005261.2 1586 167783 S1342 E G Y H Q V P S L L P A R Q P
Chimpanzee Pan troglodytes Q5IS56 1580 169881 Q1342 P G A G R P G Q Q M L G Q I S
Rhesus Macaque Macaca mulatta XP_001098108 1580 169984 Q1342 P G A G R P G Q Q M L G Q V S
Dog Lupus familis XP_540363 1589 168926 R1348 V P H Q G A G R A G Q Q M L G
Cat Felis silvestris
Mouse Mus musculus Q61602 1583 171637 Q1345 Q G P S R P G Q Q V L G Q V G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506723 1591 170747 M1353 G V G R S G Q M T L G P V S P
Chicken Gallus gallus P55879 663 73088 S427 S S K V S E E S P E A N S T T
Frog Xenopus laevis Q91661 1361 149536 G1124 V H G A P T Q G F A N N F S V
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P19538 1397 153262 M1161 T V Q D K F A M T A V G G S F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34708 1110 122786 G874 I Q E A E T A G R N V G G F G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.9 47.7 47.4 N.A. 47.5 N.A. N.A. 48.9 32.4 50.8 N.A. N.A. 22.6 N.A. 22.3 N.A.
Protein Similarity: 100 60.7 60.5 59.8 N.A. 60.7 N.A. N.A. 61.7 37.3 61 N.A. N.A. 38.3 N.A. 34.4 N.A.
P-Site Identity: 100 6.6 6.6 0 N.A. 6.6 N.A. N.A. 13.3 6.6 0 N.A. N.A. 0 N.A. 0 N.A.
P-Site Similarity: 100 26.6 26.6 6.6 N.A. 33.3 N.A. N.A. 13.3 6.6 0 N.A. N.A. 6.6 N.A. 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 20 20 0 10 20 0 10 20 10 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 10 0 10 10 10 0 0 10 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 10 0 0 10 0 0 0 10 10 10 % F
% Gly: 10 40 20 20 10 10 40 20 0 10 10 50 20 0 30 % G
% His: 0 10 10 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 10 20 30 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 20 0 20 0 0 10 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 10 20 0 0 0 % N
% Pro: 20 10 10 0 10 30 10 0 10 0 10 10 0 0 20 % P
% Gln: 10 10 10 10 10 0 20 30 30 0 10 10 30 10 0 % Q
% Arg: 0 0 0 10 30 0 0 10 10 0 0 0 10 0 0 % R
% Ser: 10 10 0 10 20 0 0 20 0 0 0 0 10 30 20 % S
% Thr: 10 0 0 0 0 20 0 0 20 0 0 0 0 10 10 % T
% Val: 20 20 0 10 0 10 0 0 0 10 20 0 10 20 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _